THE FINAL PROGRAM of RDPA2021 is described below.
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SEPTEMBER 6th 2021
· Morning ·
09.00-09.20 · Opening
RDPA1 - OMIC SCIENCES AND BIOMARKER DISCOVERY
Chairs: Vincenza Andrisano, Giancarlo Aldini
09.20-10.00 · PL1 Shedding More Light On Metabolic Alterations Associated With SARS-CoV-2 Infection
C. Barbas, San Pablo-CEU University, Madrid, Spain
10.00-10.30 · KN1 Analytical Solutions for Deep Lipidome Profiling
M. Fedorova, Universität Leipzig, Germany
10.30-10.50 · OC1 Link between serum lipid signature and prognostic factors in COVID-19 patients
M. Dei Cas, University of Milan, Italy
10.50-11.10 Break
11.10-11.40 · KN2 Advances in sampling and sample preparation for mass spectrometric determination of protein biomarkers
T. Halvorsen, University of Oslo, Norway
11.40-12.00 · OC2 Functional proteomics study of carnosine’s effect on UV-A irradiated nude mice skin
A. D’Amato, University of Milan, Italy
12.00-12.20 · OC3 Miniaturised biosampling and MS-based analysis for the assessment of biomarkers in an amyotrophic lateral sclerosis animal model
M. Protti, Alma Mater Studiorum University of Bologna, Italy
12.20-12.40 · OC4 Functional proteomics ties Calreticulin with the anti-angiogenic properties of the pyrazolyl-urea GeGe-3
E. Morretta, University of Salerno, Italy
12.40-13.00 · FC1 Plasma metabolomic and lipidomic changes in Covid-19 patients with different severity from Campania region: Preliminary investigation by a combined HRMS approach
F. Merciai, University of Salerno, Italy
FC2 Synthesis and preliminary characterization of glycan specific molecularly imprinted nanoparticles for cancer associated biomarkers
C. Contardi, University of Pavia, Italy
13.00-14.30
· Afternoon ·
RDPA2 - ANALYSIS OF BIOMOLECULES
Chairs: Ersilia De Lorenzi, Manuela Bartolini
14.30-15.10 · PL2 Antibody drug conjugates characterization: a unique analytical challenge
A. B. Valsasina, Nerviano Medical Sciences, Milan, Italy
15.10-15.40 · KN3 On the importance of accurate molecular diffusion coefficients for the assessment of mass transfer phenomena of biomolecules in liquid chromatography
D. Cabooter, University of Leuven, Belgium
15.40-16.00 · OC5 Effect of novel αS1-peptide on endothelial dysfunction and oxidative stress induced by Angiotensin II
G. Pepe, University of Salerno, Italy
16.00-16.20 Break
16.20-16.50 · KN4 Analytical Challenges in Vaccine Development and Characterization: The Case of a Novel Vaccine Against Tuberculosis
C. Temporini, University of Pavia, Italy
16.50-17.10 · OC6 Novel Fc receptor affinity chromatography characterizes therapeutic antibodies and correlates with glycan pattern and ADCC
A. Krumm, Tosoh Bioscience GmbH, Griesheim, Germany
17.10-17.30 · FC3 Direct IEX-MS for the detailed characterization of monoclonal antibody charge variants: dream or reality?
A. Murisier, University of Geneve, Switzerland
FC4 An integrated peptidomics and in silico approach for the identification of novel DPP-IV inhibitory peptides
S. Martini, University of Modena and Reggio Emilia, Italy
17.30-18.30 · Poster session · PDF download ·
SEPTEMBER 7th 2021
· Morning ·
RDPA3 - DRUG ANALYSIS
Chairs: Gabriella Massolini, Roccaldo Sardella
09.00-09.10 · In memory of Professor Sergio Pinzauti
G. Massolini, B. Chankvetadze
09.10-09.50 · PL3 Advanced Selectivity in (Bio)Pharmaceutical Analysis: New Surface Chemistries, Stationary Phase Orthogonality and Column Coupling
M. Laemmerhofer, University of Tuebingen, Germany
09-50-10.20 · KN5 Mass spectrometry based binding assays - an alternative to radioligand binding assays
G. Höfner, Ludwig-Maximilians-Universität, Munich, Germany
10.20-10.40 · OC7 Application of LEDA algorithm for the recognition of PG-P and Carbonic Anhydrase hybrids inhibitors and evaluation of their plasma stability by HPLC-MS/MS analysis
M. Pallecchi, University of Florence, Italy
10.40-10.50 · FC5 Constrained analogues of vanoxerine to treat drug addiction: biological evaluation through cerebral microdialysis coupled to HRMS
S. Franchini, University of Modena and Reggio Emilia, Italy
10.50-11.10 Break
11.10-11.40 · KN6 Recent Studies Aimed at Understanding Enantioselective Binding of Chiral Drug Enantiomers with Cyclodextrins
B. Chankvetadze, Tbilisi State University, Georgia
11.40-12.00 · OC8 A molecular dynamics study to investigate the enantioseparation mechanisms of dipeptides on Ristocetin A chiral stationary phase
A. Carotti, University of Perugia, Italy
12.00-12.20 · OC9 Development and validation of a gas chromatographic–mass spectrometric (GC–MS) method for the determination of fentanyl in blood of cancer patients
S. Montanari, University of Bologna, Italy
12.20-12.40 · OC10 Probing the Effect of Sildenafil on Progesterone and Testosterone Production exploiting a new intracellular FRET-based sensor for PDE5
Giulia Di Rocco, University of Modena and Reggio Emilia, Italy
12.40-13.00 · FC6 Physicochemical Evaluation of Carboxylic Acid Bioisosteres: Theoretical and Experimental Approaches
A. Mammoli, University of Perugia, Italy
FC7 Application of a Chiral UHPLC-MS/MS Method to the Quantitative Measurement of Cysteine Enantiomers in Mouse Plasma
S. Ferré, University of Geneve, Switzerland
13.00-14.00 Break
· Afternoon ·
14.00-14.30 · Webinar
RDPA4- CANNABIS AND CANNABINOID ANALYSIS
Chairs: Federica Pellati, Giulio Rastelli
14.30-15.00 · KN7 The Heterogeneity and Complexity of Cannabis Extracts as Antitumor Agents
D. Meiri, Technion- Israel Institute of Technology, Haifa, Israel
15.00-15.30 · KN8 Cannabis, tell me something new…
Pollastro, University of Eastern Piedmont, Novara, Italy
15.30-15.50 · OC11 Chemoselectivity of Normal Phase Stationary Phases Towards the Separation of Cannabinoids
S. Felletti, University of Ferrara, Italy
15.50-16.00 · FC8 UHPLC-HRMS analysis of non-psychoactive Cannabis sativa L. extracts and assessment of their in vitro antiproliferative activity
L. Anceschi, University of Modena and Reggio Emilia, Italy
16.00-16.20 Break
16.20-16.40 · OC12 The novel heptyl phorolic acid cannabinoids content in different Cannabis sativa L. accessions
C. Citti, CNR Nanotec, Lecce, Italy
16.40-17.00 · OC13 New Perspective in Cannabinoids Monitoring: Analysis of Medical Cannabis by MicroNIR/Chemometrics
G. Gullifa, Sapienza University of Rome, Italy
17.00-17.30 · FC9 Separation science toolbox for in depth characterization of Humulus lupulus bioactive compounds
E. Salviati, University of Salerno, Italy
FC10 High-throughput cholinesterase inhibition screening and equivalency calculation of inhibitors in traditional medicinal extracts
E. Azadniya, Justus Liebig University of Giessen, Germany
FC11 Fagus sylvatica leaves: bioactives’ sustainable recovery for animal feed
M. Formato, University of Campania, Italy
17.30-18.30 · Poster session · PDF download ·
SEPTEMBER 8th 2021
· Morning ·
RDPA5- NUTRACEUTICAL AND FOOD ANALYSIS
Chairs: Francesco Epifano, Laura Mercolini
09.00-09.30 · KN9 Validation of Analytical Methods within the EU Official Control of Contaminants in Food
R. Galarini, Istituto Zooprofilattico Sperimentale dell’Umbria e delle Marche, Perugia, Italy
09.30-09.50 · OC14 Boswellic Acids – A Comparison Of Different Techniques For Their Analysis
M. Ganzera, University of Innsbruck, Austria
09.50-10.10 · OC15 Analytical strategies to identify the bioactive molecules of bergamot leaf extract and to elucidate their mechanism of action
G. Baron, University of Milan, Italy
10.10-10.30 · OC16 Development of an accelerated stability model to estimate purple corn cob extract powder (Moradyn) shelf-life
L. Ferron, University of Pavia, Italy
10.30-10.50 · OC17 Selective Adsorption of Plant Secondary Metabolites by Solid Sorbents
S. Fiorito, University of Chieti-Pescara, Italy
10.50-11.10 Break
RDPA6 - RECENT TRENDS IN (BIO)PHARMACEUTICAL ANALYSIS
Chairs: Maria Paola Costi, Enrica Calleri
11.10-11.30 · FC12 Boosting the efficiency of the capture step in the downstream processing of biopharmaceuticals through CaptureSMB
M. Catani, University of Ferrara, Italy
FC13 A bioinformatic tool for MS/MS spectra quality assessment
M. F. Fernández, San Pablo-CEU University, Madrid, Spain
11.30-11.50 · OC18 Albumin-On-A-Chip for Personalized Screening
M. Naldi, Alma Mater Studiorum University of Bologna, Italy
11.50-12.20 · KN10 Mass Spectrometry Imaging Applied to Neuropharmacology,
P.E. Andren, Uppsala University, Sweden
12.20-13.00 · PL4 New insights in Quantitative Bioanalysis methodologies by LC-MS
S. Rudaz, University of Geneve, Switzerland
13.00-13.20 · Poster awards and closing remarks